Related Experiment Video
Updated: May 27, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
Published on: October 31, 2025
Perioperative management of the child on long-term opioids
Tim Geary1, Anna Negus, Brian J Anderson
1Department of Anaesthesia, Starship Children's Hospital, Auckland, New Zealand.
Insights
Managing children on long-term opioids requires maintaining their existing opioid regimen and using additional analgesia for acute perioperative pain. Effective strategies involve collaboration and education for optimal postoperative care and discharge planning.
Area of Science:
- Pediatric Anesthesiology
- Pain Management
- Pharmacology
Background:
- Strategies for managing children on long-term opioids are often adapted from adult guidelines.
- Perioperative opioid consumption is significantly higher in children with chronic opioid use compared to others.
- Inadequate opioid management can lead to poor pain control and withdrawal symptoms in these pediatric patients.
Purpose of the Study:
- To outline effective perioperative pain management strategies for children with long-term opioid exposure.
- To emphasize the need for maintaining a child's baseline opioid requirement during surgery.
- To highlight the importance of supplemental analgesia for acute postoperative pain.
Main Methods:
- Maintaining the child's pre-existing opioid requirement using long-acting formulations (e.g., patches, pumps).
- Administering additional analgesia for acute perioperative pain, including short-acting opioids, regional/local anesthesia, and adjuvant therapies.
- Utilizing various methods for supplemental postoperative pain relief, such as intravenous infusions, nurse-controlled analgesia, patient-controlled analgesia, or oral formulations.
Main Results:
- Perioperative opioid needs are substantially elevated in children with long-term opioid use.
- A multimodal approach combining baseline maintenance and supplemental analgesia is crucial.
- Effective management necessitates collaboration among the child, family, and healthcare teams.
Conclusions:
- Pediatric perioperative pain management for children on long-term opioids requires a tailored approach, not just dose escalation.
- Acute pain services can effectively manage these patients in the perioperative setting.
- Education for staff on specific challenges and postoperative management strategies is essential for successful outcomes and discharge planning.
Abstract:
The strategies used to manage children exposed to long-term opioids are extrapolated from adult literature. Opioid consumption during the perioperative period is more than three times that observed in patients not taking chronic opioids. A sparing use of opioids in the perioperative period results in both poor pain management and withdrawal phenomena. The child's pre-existing opioid requirement should be maintained, and acute pain associated with operative procedures should be managed with additional analgesia. This usually comprises short-acting opioids, regional or local anesthesia, and adjuvant therapies. Long-acting opioids, transdermal opioid patches, and implantable pumps can be used to maintain the regular opioid requirement. Intravenous infusion, nurse controlled analgesia, patient-controlled analgesia, or oral formulations are invaluable for supplemental requirements postoperatively. Effective management requires more than simply increasing opioid dose during this time. Collaboration of the child, family, and all teams involved is necessary. While chronic pain or palliative care teams and other staff experienced with the care of children suffering chronic pain may have helpful input, many pediatric hospitals do not have chronic pain teams, and many patients receiving long-term opioids are not palliative. Acute pain services are appropriate to deal with those on long-term opioids in the perioperative setting and do so successfully in many centers. Staff caring for such children in the perioperative period should be aware of the challenges these children face and be educated before surgery about strategies for postoperative management and discharge planning.
Related Concept Videos
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Opioid Analgesics: Morphine and Other Natural Cogeners
Analgesia and Pain Management
Parenteral Anesthetics: Overview
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Peripheral Artery Disease V: Postoperative Nursing Management