Related Experiment Video
Updated: May 27, 2026

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
Published on: May 16, 2021
Drug discovery in the 21st century
1Northeastern University, Department of Chemistry & Chemical Biology, Hurtig 102, 360 Huntington Avenue, Boston, MA 02115, USA. m.pollastri@neu.edu
Abstract:
The Advanced Pharmaceutical Chemistry conference entitled was held on 6–7 June 2011 at the Broad Institute in Cambridge, MA, USA. This 2-day conference focused on four specific areas: applying biophysical techniques to address current challenges in medicinal chemistry and drug discovery; treatment interventions for Alzheimer’s disease; drug discovery for orphan, rare and neglected diseases; and kinase drug discovery for chronic and rare diseases. The meeting attracted 80 attendees, approximately 95% of whom were drawn from the local biopharmaceutical industry.
Related Concept Videos
Drug Discovery: Overview
Pharmacogenomics: Identification of New Drug Targets
Structure-Activity Relationships and Drug Design
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence its...
Next-generation Sequencing
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.
Preclinical Development: Overview
G Protein-coupled Receptors
GPCRs are also called heptahelical, 7TM, or serpentine receptors, and consist of seven (H1-H7) transmembrane alpha-helices that span the bilayer to form a cylindrical core. The transmembrane helices are connected by three extracellular loops and three...
