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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

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Related Experiment Video

Updated: May 27, 2026

In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats

In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats

Published on: March 23, 2022

Integrating PET with behavioral neuroscience using RatCAP tomography.

Daniela Schulz¹, Paul Vaska

¹Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, NY 11794-5230, USA. dschulz@bnl.gov

Reviews in the Neurosciences

|November 22, 2011

Summary

This summary is machine-generated.

This study integrates Positron Emission Tomography (PET) with behavioral observations in freely moving rats. It simultaneously assesses spontaneous behavior and dopamine D2 receptor function, advancing behavioral neuroscience.

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Training Dogs for Awake, Unrestrained Functional Magnetic Resonance Imaging

Training Dogs for Awake, Unrestrained Functional Magnetic Resonance Imaging

Published on: October 13, 2019

Area of Science:

Neuroscience
Behavioral Neuroscience
Neuroimaging

Background:

Behavioral studies are crucial for understanding brain function and internal states.
Positron Emission Tomography (PET) offers in vivo insights into neuronal communication mechanisms.
Anesthesia in small animals for PET imaging can hinder behavioral studies.

Purpose of the Study:

To review the contributions of PET to behavioral neuroscience.
To present an integrated approach for simultaneous PET imaging and behavioral observation in freely moving rats.
To assess spontaneous behavior and dopamine D2 receptor functions concurrently.

Main Methods:

Utilized a miniature PET scanner worn on the head by rats.
Implemented a mobility system to allow for animal movement during imaging.
Integrated PET data with behavioral measures for comprehensive analysis.

Main Results:

Successfully assessed spontaneous, self-initiated behavioral activity in rats.
Simultaneously evaluated dopamine D2 receptor functions.
Demonstrated the feasibility of combining PET imaging with naturalistic behavior.

Conclusions:

The integrated PET and behavioral observation system overcomes limitations of anesthesia.
This approach enables simultaneous assessment of brain function and behavior in mobile subjects.
Advances the study of neural mechanisms underlying complex behaviors.