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Updated: May 27, 2026

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Implications of the Frequent Hemodialysis Network-Daily Trial
Kalani L Raphael1, Alfred K Cheung
1Division of Nephrology & Hypertension, University of Utah and Salt Lake City Veterans Affairs Health Care System, Salt Lake City, Utah, USA.
Abstract:
Despite many years of experience with hemodialysis, the outcomes of maintenance dialysis patients remain poor. The Frequent Hemodialysis Network-Daily (FHN-Daily) Trial found that six times per week in-center short hemodialysis decreased left ventricular mass and improved self-reported physical functioning over a 1-year intervention period compared with conventional thrice-weekly dialysis. Despite the promising results, caution is needed in the projection of these intermediate outcomes to hard clinical endpoints, such as cardiovascular events and death.
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