Related Experiment Video
Updated: May 27, 2026

08:26
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
Transrectal natural orifice translumenal endoscopic surgery (NOTES) for colorectal resection
1Gastrointestinal and Minimally Invasive Surgery Division, The Oregon Clinic, Portland, Oregon 97210, USA.
Summary
Transanal natural orifice translumenal endoscopic surgery (NOTES) offers unique advantages for intra-abdominal procedures. This research explores preclinical and clinical transanal NOTES colorectal resections, highlighting their potential.
Area of Science:
- Minimally Invasive Surgery
- Gastroenterology
- Surgical Innovation
Background:
- Natural orifice translumenal endoscopic surgery (NOTES) represents a novel surgical approach.
- Current research predominantly focuses on oral or vaginal access routes for NOTES.
- Transanal access, despite contamination concerns, presents distinct advantages for specific procedures.
Purpose of the Study:
- To present and discuss preclinical and clinical research on transanal NOTES colorectal resections.
- To evaluate the feasibility and potential of the transanal route for NOTES procedures.
Main Methods:
- Review of existing preclinical research on transanal NOTES.
- Analysis of clinical case studies and outcomes of transanal NOTES colorectal resections.
- Discussion of surgical techniques and challenges associated with the transanal approach.
Main Results:
- Demonstration of successful transanal NOTES colorectal resections in preclinical models.
- Presentation of initial clinical data supporting the safety and efficacy of transanal NOTES.
- Identification of key considerations for contamination control and surgical execution.
Conclusions:
- Transanal NOTES is a viable and promising route for colorectal surgery.
- Leveraging existing transanal surgical expertise can facilitate the advancement of NOTES.
- Further research is warranted to optimize techniques and expand clinical applications.
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