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Updated: May 27, 2026

Biochemical Measurement of Neonatal Hypoxia

Biochemical Measurement of Neonatal Hypoxia

Published on: August 24, 2011

Hemoglobinopathy newborn screening knowledge of physicians.

Kirsty M McWalter¹, Elaine M White, Donald K Hayes

¹Department of Health Genetics Program, Children With Special Needs Branch, Hawai'i Department of Health, Honolulu, Hawai'i 96816, USA. kirsty@hawaiigenetics.org

American Journal of Preventive Medicine

|November 22, 2011

Summary

Pediatrician knowledge of inherited hemoglobinopathies and newborn screening (NBS) varied, indicating a need for targeted education. This study assessed baseline knowledge to inform the development of effective genetics and NBS training programs.

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Area of Science:

Medical Genetics
Pediatrics
Public Health

Background:

Hawai'i's diverse population includes individuals of Asian descent, with a notable 2% infant incidence of alpha-thalassemia trait.
The Hawai'i Genetics Program offers crucial genetics services, including a hemoglobinopathy clinic and provider education initiatives.
Understanding inherited hemoglobinopathies is vital for public health, particularly in diverse populations with higher genetic disease prevalence.

Purpose of the Study:

To evaluate the baseline knowledge of pediatricians regarding inherited hemoglobinopathies.
To identify specific knowledge gaps that can inform the development of targeted educational programs for healthcare providers.
To assess pediatrician understanding of newborn screening (NBS) panels for hemoglobinopathies.

Main Methods:

A survey was administered to pediatricians in Hawai'i, San Francisco (SF), and Salt Lake City (SLC) between 2008-2009.
The survey assessed knowledge of hemoglobinopathies and NBS, with 660 surveys mailed and results analyzed in 2011.
Knowledge scores were calculated based on responses to four key questions regarding hemoglobinopathies and NBS.

Main Results:

A response rate of 34% (226 pediatricians) was achieved, with significant representation from Hawai'i (113).
Overall, 89.4% of participants demonstrated good or perfect knowledge scores, yet specific gaps were identified.
Key findings include 32.4% administering iron to all anemic patients and 29% incorrectly believing beta-thalassemia is not detected by NBS.

Conclusions:

Significant knowledge disparities in hemoglobinopathy and NBS understanding exist among and within pediatrician populations.
These findings highlight opportunities for developing tailored educational interventions to improve healthcare provider knowledge.
The study results will guide the creation of educational materials to ensure a competent healthcare workforce in genetics and NBS.