Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ion-Exchange Chromatography01:09

Ion-Exchange Chromatography

Ion-exchange chromatography, or IEC, is a technique for separating ions based on their affinity for the stationary phase. The stationary phase is a cross-linked polymer resin with covalently attached ionic functional groups. The functional groups can be either positively charged (cation exchangers) or negatively charged (anion exchangers). A cation exchanger consists of a polymeric anion and active cations, while an anion exchanger is a polymeric cation with active anions. The choice of...
Principles Of Column Chromatography01:13

Principles Of Column Chromatography

The chromatography technique was first invented in 1901 by Michael S. Tswett, a Russian botanist, to separate plant pigments using organic solvents. Further, in 1941, Archer John Porter Martin and R. L. M. Synge modified the technique by packing silica gel into a column. A mixture of amino acids was then separated on the packed column using chloroform and water mixture as the mobile phase. This was the first report on column chromatography. At present, column chromatography is a widely used...
High-Performance Liquid Chromatography: Elution Process01:05

High-Performance Liquid Chromatography: Elution Process

In High-Performance Liquid Chromatography (HPLC), the elution process is critical to the separation of analytes and the quality of chromatographic results. Elution describes how compounds move through the column and separate based on their interactions with the mobile and stationary phases. This process determines the resolution, peak shape, and retention times in the chromatogram, which are essential for identifying and quantifying components in complex mixtures. Understanding the elution...
Gas Chromatography: Types of Detectors-II01:19

Gas Chromatography: Types of Detectors-II

In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...
Extraction: Advanced Methods00:56

Extraction: Advanced Methods

Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is formed in...
Optimizing Chromatographic Separations01:15

Optimizing Chromatographic Separations

Optimizing chromatographic separations is crucial for obtaining clean separations in a minimum amount of time. Optimization is required for several factors, including kinetic effects related to band broadening, plate height, capacity factor, and separation factor.
Band broadening refers to spreading solute bands as they travel through the column. This broadening can impact resolution. Plate height (H) represents the length required for one theoretical plate. A lower plate height corresponds to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to "Rapid and Accurate Determination of <sup>226</sup>Ra from Drinking Water Using Macropa-Mediated Cloud Point Extraction Coupled with ICP-MS/MS".

Analytical chemistry·2026
Same author

Rapid and Accurate Determination of <sup>226</sup>Ra from Drinking Water Using Macropa-Mediated Cloud Point Extraction Coupled with ICP-MS/MS.

Analytical chemistry·2026
Same author

Metrology of rare earths and other elements in waste fluorescent lamp powder - A methodological comparison.

Analytica chimica acta·2026
Same author

Accurate measurements of lead using isotope dilution calibration curve method with the accounting for natural isotopic variations.

Analytica chimica acta·2026
Same author

Exploring patients' and caregivers' experience of therapeutic patient education in rare diseases: A qualitative study.

Patient education and counseling·2026
Same author

Aspects of Agency and their Uses in Psychoanalysis.

Journal of the American Psychoanalytic Association·2026

Related Experiment Video

Updated: May 27, 2026

Separation of Uranium and Thorium for 230Th-U Dating of Submarine Hydrothermal Sulfides
08:43

Separation of Uranium and Thorium for 230Th-U Dating of Submarine Hydrothermal Sulfides

Published on: May 20, 2019

Neptunium(III) application in extraction chromatography.

Nicolas Guérin1, Kenny Nadeau, Dominic Larivière

  • 1Laboratoire de Radioécologie, Département de chimie, Université Laval, 1045 Avenue de la Médecine, Québec, QC, Canada, G1V 0A6. nicolas.guerin.1@ulaval.ca

Talanta
|November 22, 2011
PubMed
Summary

This study presents a new method for separating Neptunium (Np) using valence adjustment to Np(III). This process effectively separates Np from Uranium (U) and removes chromium impurities using specialized resins.

More Related Videos

On-line Analysis of Nitrogen Containing Compounds in Complex Hydrocarbon Matrixes
07:49

On-line Analysis of Nitrogen Containing Compounds in Complex Hydrocarbon Matrixes

Published on: August 5, 2016

A Novel Technique for Raman Analysis of Highly Radioactive Samples Using Any Standard Micro-Raman Spectrometer
07:52

A Novel Technique for Raman Analysis of Highly Radioactive Samples Using Any Standard Micro-Raman Spectrometer

Published on: April 12, 2017

Related Experiment Videos

Last Updated: May 27, 2026

Separation of Uranium and Thorium for 230Th-U Dating of Submarine Hydrothermal Sulfides
08:43

Separation of Uranium and Thorium for 230Th-U Dating of Submarine Hydrothermal Sulfides

Published on: May 20, 2019

On-line Analysis of Nitrogen Containing Compounds in Complex Hydrocarbon Matrixes
07:49

On-line Analysis of Nitrogen Containing Compounds in Complex Hydrocarbon Matrixes

Published on: August 5, 2016

A Novel Technique for Raman Analysis of Highly Radioactive Samples Using Any Standard Micro-Raman Spectrometer
07:52

A Novel Technique for Raman Analysis of Highly Radioactive Samples Using Any Standard Micro-Raman Spectrometer

Published on: April 12, 2017

Area of Science:

  • Nuclear Chemistry
  • Radiochemistry
  • Separation Science

Background:

  • Actinide separation is crucial for nuclear fuel reprocessing and waste management.
  • Traditional methods face challenges with selectivity and efficiency for specific actinides like Neptunium.
  • Valence adjustment offers a promising route to enhance separation factors.

Purpose of the Study:

  • To develop and validate a novel extraction chromatography method for Neptunium separation.
  • To achieve selective separation of Neptunium from Uranium using Np(III) valence state.
  • To effectively remove chromium impurities introduced during the reduction process.

Main Methods:

  • Extraction chromatography utilizing TEVA and DGA resins.
  • Valence adjustment of Neptunium(IV) to Neptunium(III) using Chromium(II).
  • UV-visible spectroscopy and kinetic studies to confirm Np(III) formation and Cr(II) role.

Main Results:

  • Selective separation of Np(III) from U(IV) achieved with high recovery (99 ± 7%) on TEVA resin.
  • Chromium(II) confirmed as the sole reductant for Np(IV) to Np(III).
  • High decontamination factors (up to 7.3 × 10^4) for chromium impurities using DGA resin.

Conclusions:

  • The proposed TEVA/DGA resin system with Np(III) valence adjustment is effective for actinide separation.
  • The method is robust, allowing Cr(II) solution preparation shortly before use.
  • This strategy offers an efficient and selective approach for Neptunium purification.