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Related Experiment Video

Updated: May 27, 2026

Human Pancreatic Islet Isolation: Part I: Digestion and Collection of Pancreatic Tissue
11:54

Human Pancreatic Islet Isolation: Part I: Digestion and Collection of Pancreatic Tissue

Published on: May 26, 2009

Human islet distribution program for basic research at a single center.

T Kin1, D O'Gorman, A Schroeder

  • 1Clinical Islet Laboratory and Clinical Islet Transplant Program, University of Alberta, Edmonton, Alberta, Canada. tkin@ualberta.ca

Transplantation Proceedings
|November 22, 2011
PubMed
Summary
This summary is machine-generated.

The Clinical Islet Laboratory provides human islets for diabetes research, distributing millions of islet equivalents (IEQs) annually. Researchers now receive smaller, more frequent shipments, enhancing experimental sample sizes.

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Last Updated: May 27, 2026

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Area of Science:

  • Endocrinology
  • Cell Biology
  • Transplantation Research

Background:

  • The Clinical Islet Laboratory at the University of Alberta/Alberta Health Services provides human islets for basic research.
  • Islet preparations not meeting transplantation criteria are distributed for research purposes.
  • This report focuses on islet distribution for diabetes research over a three-year period.

Purpose of the Study:

  • To highlight the islet distribution activity for diabetes research over a 3-year period.
  • To analyze trends in islet distribution, including quantity, frequency, and researcher engagement.
  • To assess the supply-versus-demand ratio for research-grade human islets.

Main Methods:

  • Data collection on islet distribution from 2008 to 2010.
  • Quantification of islet equivalents (IEQs) distributed per shipment and annually.
  • Tracking the number of researchers and shipment frequency.

Main Results:

  • In 2010, 6.3 million IEQs were distributed in 127 shipments to 8 researchers.
  • The number of research preparations and researchers remained stable from 2008-2010.
  • Researchers received fewer IEQs per shipment but shipments were more frequent, aligning with research needs.

Conclusions:

  • Islet distribution for research has remained stable in terms of total productivity.
  • A shift towards smaller, more frequent islet shipments benefits researchers by increasing sample size.
  • The current supply-demand ratio for research islets is considered appropriate.