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Updated: May 27, 2026

Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
Published on: September 13, 2014
Acute liver failure secondary to khat (Catha edulis)-induced necrotic hepatitis requiring liver transplantation: case
P Roelandt1, C George, F d'Heygere
1Hepatology Department, University Hospitals Leuven, Leuven, Belgium. philip.roelandt@uzleuven.be
Abstract:
We describe the case of a 26-year-old man with acute liver failure secondary to ingestion of khat (Catha edulis) leaves. In fact, this is the first case of acute liver failure due to khat reported outside the United Kingdom. The combination of specific epidemiologic data (young man of East African origin) and clinical features (central nervous system stimulation, withdrawal reactions, toxic autoimmune-like hepatitis) led to the diagnosis. Mechanisms of action and potential side effects of khat are elaborated on.
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