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Updated: May 27, 2026
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Ferromagnetic Bare Metal Stent for Endothelial Cell Capture and Retention
Published on: September 18, 2015
Current state of the absorbable metallic (magnesium) stent
1Department of Internal Medicine, Division of Cardiology, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010, USA. ron.waksman@medstar.net
Summary
BIOTRONIK
Area of Science:
- Biomaterials Engineering
- Cardiovascular Devices
- Medical Technology
Background:
- Absorbable metal stents offer potential advantages over traditional permanent stents.
- Magnesium alloys are being explored for their biocompatibility and mechanical properties in stenting applications.
Purpose of the Study:
- To review the development and progress of BIOTRONIK's absorbable metal stent (AMS) technology.
- To highlight the evolution from the first generation (AMS-1) to the latest drug-eluting version (AMS-3).
Main Methods:
- Review of preclinical and clinical data for successive generations of magnesium alloy stents.
- Evaluation of mechanical properties, degradation rates, scaffolding, and efficacy.
Main Results:
- AMS-1 demonstrated feasibility and safety in human applications.
- AMS-2.1 showed improved animal outcomes with slower degradation and optimized design.
- Preclinical data for the drug-eluting AMS-3 are encouraging.
Conclusions:
- BIOTRONIK's absorbable magnesium alloy stent technology has shown progressive improvements.
- Further clinical investigation of the drug-eluting AMS-3 is planned, indicating continued advancement in the field.
