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Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
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Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
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Viral Mutations

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Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
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Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus
10:35

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

Published on: May 31, 2020

Chikungunya: a re-emerging virus.

Felicity J Burt1, Micheal S Rolph, Nestor E Rulli

  • 1Department of Medical Microbiology and Virology, National Health Laboratory Services Universitas and University of the Free State, Bloemfontein, South Africa. burtfj@ufs.ac.za

Lancet (London, England)
|November 22, 2011
PubMed
Summary
This summary is machine-generated.

Chikungunya virus, transmitted by Aedes mosquitoes, is causing widespread outbreaks globally. This seminar reviews its clinical features, pathogenesis, diagnostics, and treatments for this re-emerging infectious disease.

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Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus
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Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
06:18

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

Area of Science:

  • * Virology and Epidemiology
  • * Infectious Diseases and Public Health

Background:

  • * Chikungunya virus (CHIKV) re-emergence in Africa, Asia, and Indian Ocean Islands causing large human outbreaks.
  • * CHIKV is transmitted by Aedes spp. mosquitoes, presenting with fever, rash, and severe arthralgia.
  • * Global spread of Aedes albopictus increases risk in Europe and the Americas.

Purpose of the Study:

  • * To focus on the re-emergence of chikungunya.
  • * To discuss clinical manifestations and pathogenesis of CHIKV-induced arthralgia.
  • * To review diagnostic techniques and treatment modalities.

Main Methods:

  • * Literature review and synthesis of current knowledge on chikungunya.
  • * Analysis of epidemiological data on CHIKV outbreaks.
  • * Overview of clinical case studies and pathogenesis research.

Main Results:

  • * CHIKV causes significant morbidity and mortality, with persistent arthralgia being a key feature.
  • * Increased global mobility and mosquito vector spread facilitate wider CHIKV transmission.
  • * Current diagnostic and treatment strategies are under review.

Conclusions:

  • * Chikungunya poses a growing global health threat due to its re-emergence and spread.
  • * Understanding CHIKV pathogenesis is crucial for effective management.
  • * Continuous monitoring and development of control strategies are essential.