Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Redox- and Photo-Responsive Fe<sup>3+/2+</sup>-Cross-Linked Carboxymethyl Cellulose Methacrylate Dissipative Gels: Synthesis and Applications.

ACS applied materials & interfaces·2026
Same author

Intracellular logic computing with DNA tetrahedron processors enables precision cancer theranostics.

Signal transduction and targeted therapy·2026
Same author

Dictated cell adhesion and migration using microfluidic-controlled synthetic hydrogels exhibiting programmable viscoelasticities.

Journal of materials chemistry. B·2026
Same author

Photoactivated Signaling Networks using DNA-Based Synthetic Organelles as Biomimetic Protocells.

Angewandte Chemie (International ed. in English)·2026
Same author

Dynamic Switchable and Transient DNA Condensates Driven by Aptamer-Ligand or Ion-Nucleobase Bridged Complexes.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Allosteric ligand-aptamer complexes orchestrate supramolecular or transient catalytic, transcription and fibrinogenesis processes.

Chemical science·2026
Same journal

Peptidomics in the Spotlight: Advanced Sample Treatment Techniques and Analytical Insights.

Advances in experimental medicine and biology·2026
Same journal

Methods for the Investigation of Protein-Ligands Interactions.

Advances in experimental medicine and biology·2026
Same journal

Sample Preparation Strategies for Microbial Cell Surface Proteomics: Integrating Shaving and Shotgun Approaches.

Advances in experimental medicine and biology·2026
Same journal

Proteomic Sample Preparation for the Petroleum Industry: A Biocorrosion Case Study.

Advances in experimental medicine and biology·2026
Same journal

Proteomic and Functional Comparison of Extracellular Vesicles from Wild-Type and Lyn-Deficient Stromal Cells.

Advances in experimental medicine and biology·2026
Same journal

Proteomic Analysis of Histone Sequence Variants and Post-translationally Modified Forms.

Advances in experimental medicine and biology·2026
See all related articles

Related Experiment Video

Updated: May 27, 2026

DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
07:16

DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition

Published on: February 9, 2024

DNA nanotechnology.

Ofer I Wilner1, Bilha Willner, Itamar Willner

  • 1Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel.

Advances in Experimental Medicine and Biology
|November 22, 2011
PubMed
Summary
This summary is machine-generated.

DNA nanotechnology leverages nucleic acid structures for advanced applications. This field enables novel biosensors, ultrasensitive DNA detection, functional DNA machines, and programmed protein positioning for enzyme cascades.

More Related Videos

Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

Related Experiment Videos

Last Updated: May 27, 2026

DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
07:16

DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition

Published on: February 9, 2024

Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Molecular Biology

Background:

  • Nucleic acid base sequences dictate biopolymer structure and function.
  • DNA nanotechnology is a rapidly advancing field utilizing these properties.
  • Nucleic acid nanostructures form the foundation for innovative applications.

Purpose of the Study:

  • To highlight key advances in DNA nanotechnology.
  • To showcase the versatility of nucleic acid nanostructures.
  • To illustrate the potential of DNA-based platforms.

Main Methods:

  • Integration of Hemin/G-quadruplex DNA nanostructures with electrode surfaces and quantum dots.
  • Encoding structural information into DNA for autonomous replication.
  • Designing DNA nanostructures for programmable molecular machines.
  • Self-assembly of DNA nanostructures for protein positioning and enzyme cascade activation.

Main Results:

  • Development of novel electrochemical and optical bioanalytical platforms for DNA sensing.
  • Achieved ultrasensitive DNA detection through autonomous replication processes.
  • Tailored functional DNA machines, including tweezers, walkers, and steppers.
  • Programmed positioning of proteins and activation of enzyme cascades using self-assembled DNA nanostructures.

Conclusions:

  • DNA nanotechnology offers powerful tools for biosensing and molecular manipulation.
  • Nucleic acid nanostructures enable the creation of sophisticated DNA-based devices.
  • This field holds significant promise for future bioanalytical and biotechnological innovations.