The NIH National Center for Integrative Biomedical Informatics (NCIBI)

Area of Science:

• Biomedical Informatics
• Computational Biology
• Data Science

Background:

• The National Center for Integrative and Biomedical Informatics (NCIBI) is part of the National Centers for Biomedical Computing (NCBC).
• NCIBI supports biomedical researchers in accessing information and performing data analysis.
• This enables the creation of computational and knowledge models for biological systems.

Purpose of the Study:

• To address Driving Biological Problems (DBPs) through advanced informatics.
• To develop and provide software tools for data analysis and visualization.
• To foster collaboration and training in biomedical informatics.

Main Methods:

• Utilizing a suite of software tools for exploratory analysis, concept visualization, and literature searches.
• Developing core database and web services resources.
• Collaborating with institutions like the Research Centers at Minority Institutions (RCMI) for training and outreach.

Main Results:

• Successfully supported research on DBPs including prostate cancer, diabetes complications, bipolar disorder, and obesity.
• Developed a range of software tools and data resources for the research community.
• Established collaborative training programs and annual workshops.

Conclusions:

• NCIBI plays a crucial role in advancing biomedical research through informatics support.
• Future directions emphasize the TranSMART initiative for improved data sharing and analysis.
• Continued collaboration is key to addressing complex biological challenges.