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A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus
Published on: June 23, 2022
Fatal outcome of tick-borne encephalitis - a case series
Joanna Zajkowska1, Piotr Czupryna, Sławomir Pancewicz
1Department of Infectious Diseases and Neuroinfections, Medical University of Białystok, Białystok. annamoniuszko@op.pl
Abstract:
Tick-borne encephalitis (TBE) is a disease which may present as meningitis, encephalomeningitis and myeloencephalomeningitis. The course of the disease is usually mild although it may result in the patient's death in 1-4% of cases. Patients with myeloencephalomeningitis are the most endangered group, but also encephalomeningitis may have a fatal outcome. There are many risk factors which influence the severity of TBE, including patient's age, immunosuppression and concomitant diseases. We present four cases of patients who died because of TBE. The aim of the paper was to underline that in elderly patients or patients suffering from chronic diseases and additional infections, special attention should be paid to their treatment, including mechanical ventilation and steroid use.
Insights
Tick-borne encephalitis (TBE) can be fatal, especially in elderly patients or those with chronic conditions. Prompt medical attention and supportive care, including mechanical ventilation and steroids, are crucial for high-risk individuals.
Area of Science:
- Neuroscience
- Infectious Diseases
- Public Health
Background:
- Tick-borne encephalitis (TBE) is a viral infection affecting the central nervous system.
- TBE can manifest as meningitis, encephalomeningitis, or myeloencephalomeningitis, with varying severity.
- While typically mild, TBE has a mortality rate of 1-4%, with specific patient groups at higher risk.
Observation:
- This paper details four fatal cases of TBE.
- Myeloencephalomeningitis and encephalomeningitis presentations pose significant risks.
- Risk factors include advanced age, immunosuppression, and co-existing medical conditions.
Findings:
- Elderly patients and those with chronic diseases are particularly vulnerable to severe TBE outcomes.
- Fatalities underscore the need for vigilant management in at-risk populations.
- Aggressive treatment strategies, potentially including mechanical ventilation and steroid therapy, are vital.
Implications:
- Highlights the critical need for heightened clinical awareness of TBE severity in vulnerable patient groups.
- Emphasizes the importance of tailored, intensive treatment protocols for severe TBE cases.
- Informs public health strategies regarding TBE prevention and management, particularly for at-risk demographics.
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