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Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
Long-term Potentiation01:25

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
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Long-term Potentiation01:35

Long-term Potentiation

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Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
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Role of Neurotransmitters in Memory01:23

Role of Neurotransmitters in Memory

Neurotransmitters are integral to the brain's communication system, enabling neurons to transmit signals across synapses. This chemical exchange underpins various cognitive functions, including memory processes. The role of neurotransmitters in memory is multifaceted, influencing the encoding, consolidation, and retrieval of memories through their action on different neural circuits.
 Glutamate and Synaptic Plasticity
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Information Processing Approach01:30

Information Processing Approach

The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is also...

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Related Experiment Video

Updated: May 27, 2026

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
07:01

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

Dopamine, working memory, and training induced plasticity: implications for developmental research.

Stina Söderqvist1, Sissela Bergman Nutley, Myriam Peyrard-Janvid

  • 1Department of Neuroscience and Stockholm Brain Institute, Karolinska Institutet, Stockholm, Sweden. stina.soderqvist@ki.se

Developmental Psychology
|November 23, 2011
PubMed
Summary
This summary is machine-generated.

Dopamine influences working memory (WM) capacity and cognitive plasticity. Genetic variations in the dopamine transporter gene (DAT1) affect how children improve WM and fluid intelligence through cognitive training.

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Published on: September 20, 2020

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Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Genetics

Background:

  • Working memory (WM) deficits are common in neuropsychiatric disorders.
  • Dopamine is crucial for WM function and capacity enhancement.
  • Both pharmacological and behavioral interventions impact dopaminergic systems.

Purpose of the Study:

  • To review the role of dopamine in WM functioning and cognitive plasticity.
  • To investigate the influence of the dopamine transporter gene (DAT1) on WM improvements.

Main Methods:

  • Review of existing literature on dopamine and WM.
  • Analysis of novel data on DAT1 gene variations in children undergoing cognitive training.

Main Results:

  • Dopamine plays a significant role in WM development and cognitive plasticity.
  • Variation in the DAT1 gene impacts WM and fluid intelligence gains in preschool children after cognitive training.

Conclusions:

  • Dopamine is a key factor in cognitive plasticity.
  • Genetic factors, specifically DAT1, modulate the effectiveness of cognitive training for improving WM and intelligence.