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EGFR isoforms in exosomes as a novel method for biomarker discovery in pancreatic cancer

W Tristram Arscott1, Kevin A Camphausen

  • 1Radiation Oncology Branch, National Cancer Institute, Bethesda, MD 20892, USA.

Biomarkers in Medicine
|November 23, 2011
PubMed
Abstract

No abstract available in PubMed .

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Overview of Exosomes01:36

Overview of Exosomes

Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...