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Updated: May 27, 2026

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Published on: September 7, 2022
Hip artroplasty: a transient reason not to be pregnant
Nicola Maffulli1, Angelo Del Buono, Vincenzo Denaro
1Centre for Sports and Exercise Medicine, Barts and The London School of Medicine and Dentistry, London, UK. n.maffulli@qmul.ac.uk
Abstract:
Metal implants corrode and release metal ions, cobalt and chromium, which, in turn, may cause systemic toxicity, mostly in the first few months from implantation of metal-on-metal hip arthroplasty. At the time of delivery, the placenta reduces the passage of cobalt and chromium ions released from metal-on-metal prosthesis. From a biomechanical view point, hip replacement should not be considered a contraindication for pregnancy or for spontaneous delivery, and does not seem to have any negative effects in terms of risk of dislocation, loosening, fracture, or revision surgery, neither negative effects on clinical and functional outcomes. The long-term biological consequences of exposure to Co-Cr particles and ions remain largely unknown.

