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The In ovo CAM-assay as a Xenograft Model for Sarcoma

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Angiosarcoma-like presentation of pacemaker-related vascular proliferation.

J S Ringrose¹, T Banerjee, P R Hull

¹Division of General Internal Medicine, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. jennifer.ringrose@ualberta.ca

Clinical and Experimental Dermatology

|November 24, 2011

Summary

A rare vascular lesion, reticular telangiectatic erythema, can occur after pacemaker procedures. This benign condition typically resolves on its own over time.

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Area of Science:

Dermatology
Cardiology

Background:

Vascular lesions can arise after implantation of medical devices like pacemakers.
Reticular telangiectatic erythema is a known, though less common, post-implantation vascular proliferation.

Observation:

A 90-year-old male developed a rapidly growing vascular lesion post-pacemaker generator change.
Initial rapid growth raised concern for angiosarcoma.

Findings:

The lesion was diagnosed as reticular telangiectatic erythema, a benign vascular proliferation.
The condition, appearing weeks to years after device implantation, is typically static or regresses.
In this case, the vascular proliferation resolved almost completely within one year.

Implications:

Reticular telangiectatic erythema is a benign differential diagnosis for vascular lesions after pacemaker procedures.
Awareness of this condition can prevent misdiagnosis and unnecessary aggressive treatment.
The benign nature and self-resolving course of this vascular proliferation are important clinical considerations.