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Updated: May 27, 2026

The In ovo CAM-assay as a Xenograft Model for Sarcoma
Published on: July 17, 2013
Angiosarcoma-like presentation of pacemaker-related vascular proliferation
J S Ringrose1, T Banerjee, P R Hull
1Division of General Internal Medicine, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. jennifer.ringrose@ualberta.ca
Abstract:
A 90-year-old man presented with a rapidly growing vascular lesion after a pacemaker generator change. The rapid growth suggested a possible angiosarcoma. A less dramatic presentation of vascular proliferation has been described as reticular telangiectatic erythema, which has been reporting following insertion of pacemakers, implantable cardioverter defibrillators, and drug-delivery devices. The onset of the disorder is described as weeks to years after implantation or generator change. It is a benign condition that generally remains static or regresses over time. The vascular proliferation noted in this case resolved almost completely over a period of 1 year.
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