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Lobar atrophy with pontine neuronal chromatolysis ("ballooned" neurons)
C F Lippa1, T W Smith, U DeGirolami
1Department of Pathology, (Neuropathology), University of Massachusetts Medical Center, Worcester 01665.
Human Pathology
|October 1, 1990
Abstract:
A 64-year-old man developed progressive dementia over a period of 11 years. Postmortem examination showed severe atrophy of the temporal lobes of the brain with extensive neuronal loss and a remarkable alteration of the neuronal perikaryon--the "ballooned" neuron--restricted to the nuclei of the basis pontis. No neuritic plaques, neurofibrillary tangles, or Pick bodies were seen.