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Updated: May 27, 2026

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers
Published on: August 31, 2021
New experimental limits on non-Newtonian forces in the micrometer range
A O Sushkov1, W J Kim, D A R Dalvit
1Department of Physics, Yale University, P.O. Box 208120, New Haven, Connecticut 06520-8120, USA. alex@harvard.physics.edu
Abstract:
We report measurements of the short-range forces between two macroscopic gold-coated plates using a torsion pendulum. The force is measured for separations between 0.7 and 7 μm and is well described by a combination of the Casimir force, including the finite-temperature correction, and an electrostatic force due to patch potentials on the plate surfaces. We use our data to place constraints on the Yukawa-type "new" forces predicted by theories with extra dimensions. We establish a new best bound for force ranges 0.4-4 μm and, for forces mediated by gauge bosons propagating in (4+n) dimensions and coupling to the baryon number, extract a (4+n)-dimensional Planck scale lower limit of M(*)>70 TeV.

