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Updated: May 27, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Vein of Galen malformations: epidemiology, clinical presentations, management
Pablo F Recinos1, Gazanfar Rahmathulla, Monica Pearl
1Division of Pediatric Neurosurgery, The Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA.
Abstract:
The vein of Galen aneurysmal malformation is a congenital vascular malformation that comprises 30% of the pediatric vascular and 1% of all pediatric congenital anomalies. Treatment is dependent on the timing of presentation and clinical manifestations. With the development of endovascular techniques, treatment paradigms have changed and clinical outcomes have significantly improved. In this article, the developmental embryology, clinical features and pathophysiology, diagnostic workup, and management strategies are reviewed.
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