Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retraction Note: Retinal degeneration driven by brain-derived neurotrophic factor deficiency in microglia and T-lymphocytes.

Scientific reports·2026
Same author

Multifocal intraocular lenses in refractive lens exchange: Guidelines to optimize their use and indications.

Archivos de la Sociedad Espanola de Oftalmologia·2026
Same author

Machine Learning-Based Prediction of Long-Term Intraocular Pressure Fluctuations in Open-Angle Glaucoma.

Ophthalmology science·2026
Same author

Ray-Tracing-Based Intraocular Lens Power Calculation in Combined Cataract Surgery and Descemet Membrane Endothelial Keratoplasty.

Clinical & experimental ophthalmology·2026
Same author

Balanced Extended Vision Procedure: Preclinical Analysis of a Non-diffractive Approach to Full Range of Vision After Cataract Surgery.

Journal of refractive surgery (Thorofare, N.J. : 1995)·2026
Same author

Long-Term Patient Acceptability and Adherence to Suprachoroidal Telemetric Intraocular Pressure Monitoring in Glaucoma.

Journal of glaucoma·2026

Related Experiment Video

Updated: May 27, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

Optimized constants for an ultraviolet light-adjustable intraocular lens.

Ina Conrad-Hengerer1, H Burkhard Dick, Werner W Hütz

  • 1Center for Vision Science, Ruhr University Eye Clinic, Bochum, Bad Hersfeld, Germany.

Journal of Cataract and Refractive Surgery
|November 24, 2011
PubMed
Summary

Optimized constants improve intraocular lens (IOL) power calculations for light-adjustable IOLs, reducing refractive prediction errors. This allows for more accurate outcomes after cataract surgery.

More Related Videos

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries
04:59

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Scanning Light Scattering Profiler (SLPS) Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses
06:55

Scanning Light Scattering Profiler (SLPS) Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

Published on: June 6, 2017

Related Experiment Videos

Last Updated: May 27, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries
04:59

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Scanning Light Scattering Profiler (SLPS) Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses
06:55

Scanning Light Scattering Profiler (SLPS) Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

Published on: June 6, 2017

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Optical Science

Background:

  • Cataract surgery involves phacoemulsification and intraocular lens (IOL) implantation.
  • Accurate IOL power calculation is crucial for achieving desired refractive outcomes.
  • Light-adjustable IOLs offer post-operative refractive correction capabilities.

Purpose of the Study:

  • To assess the accuracy of standard IOL power calculation formulas.
  • To determine optimal adjusted constants for light-adjustable IOLs.
  • To minimize refractive prediction errors in cataract surgery.

Main Methods:

  • A cohort study evaluated 125 eyes undergoing phacoemulsification with light-adjustable IOL implantation.
  • IOLMaster measurements were taken pre- and post-operatively.
  • Refractive prediction errors were analyzed using standard and optimized IOL power calculation formulas.

Main Results:

  • Without optimized constants, standard formulas (SRK/T, Hoffer Q, Holladay 1) showed significant hyperopic prediction errors (0.86-0.98 D absolute error).
  • With optimized constants, all tested formulas achieved a mean prediction error of 0.00 D (±0.63-0.66 D).
  • Optimized constants significantly improved the accuracy of IOL power calculations.

Conclusions:

  • Optimized constants are essential for accurate refractive outcomes with light-adjustable IOLs.
  • A slight hyperopic shift may be anticipated when using optimized constants.
  • These findings aid in refining IOL power calculations for enhanced visual results.