Iron deficiency risk in children: discrepancy between dietary and biochemical assessments

V Arija1, J Salas, J Fernández-Ballart

  • 1Department of Medicine and Surgery, Barcelona University, Reus, Spain.

Insights

Dietary iron intake assessments may overestimate iron deficiency risk in children. Biochemical iron status is a more reliable indicator, especially for targeted health programs.

Area of Science:

  • Pediatric Nutrition
  • Public Health
  • Biochemistry

Background:

  • Iron deficiency is a significant global health concern in children and adolescents.
  • Accurate assessment of iron status is crucial for effective public health interventions.
  • Dietary intake assessments are commonly used but may not always reflect true iron status.

Purpose of the Study:

  • To investigate the prevalence of iron deficiency in children and adolescents using both dietary intake and biochemical markers.
  • To compare the accuracy of dietary assessment versus biochemical assessment in identifying iron deficiency risk.
  • To inform the design of health education programs by evaluating assessment methodologies.

Main Methods:

  • A random sample of 300 children and adolescents (0.5-16 years) from Spain participated.
  • Dietary iron intake was assessed, and biochemical iron status parameters (red cell volume, erythrocyte protoporphyrin, transferrin saturation, serum ferritin) were measured.
  • Data were analyzed for age and sex differences in iron intake and iron status.

Main Results:

  • Dietary assessment indicated a high percentage of children with iron intake below recommended levels (24-77%) and individual requirements (7-41%).
  • Biochemical assessment revealed a lower overall prevalence of iron deficiency (0-23.3%).
  • The highest biochemical iron deficiency prevalence (23.3%) was observed in children aged 6-24 months, contrasting with dietary assessment findings.

Conclusions:

  • Dietary iron intake assessment may overestimate the risk of iron deficiency in pediatric populations.
  • Biochemical iron status assessment provides a more accurate measure of iron deficiency prevalence.
  • Health program strategies should not rely solely on nutritional intake assessments; biochemical validation is recommended.

Related Concept Videos

Disorders of Erythrocytes01:27

Disorders of Erythrocytes

Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Minerals01:26

Minerals

Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...