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Iron deficiency risk in children: discrepancy between dietary and biochemical assessments
V Arija1, J Salas, J Fernández-Ballart
1Department of Medicine and Surgery, Barcelona University, Reus, Spain.
Insights
Dietary iron intake assessments may overestimate iron deficiency risk in children. Biochemical iron status is a more reliable indicator, especially for targeted health programs.
Area of Science:
- Pediatric Nutrition
- Public Health
- Biochemistry
Background:
- Iron deficiency is a significant global health concern in children and adolescents.
- Accurate assessment of iron status is crucial for effective public health interventions.
- Dietary intake assessments are commonly used but may not always reflect true iron status.
Purpose of the Study:
- To investigate the prevalence of iron deficiency in children and adolescents using both dietary intake and biochemical markers.
- To compare the accuracy of dietary assessment versus biochemical assessment in identifying iron deficiency risk.
- To inform the design of health education programs by evaluating assessment methodologies.
Main Methods:
- A random sample of 300 children and adolescents (0.5-16 years) from Spain participated.
- Dietary iron intake was assessed, and biochemical iron status parameters (red cell volume, erythrocyte protoporphyrin, transferrin saturation, serum ferritin) were measured.
- Data were analyzed for age and sex differences in iron intake and iron status.
Main Results:
- Dietary assessment indicated a high percentage of children with iron intake below recommended levels (24-77%) and individual requirements (7-41%).
- Biochemical assessment revealed a lower overall prevalence of iron deficiency (0-23.3%).
- The highest biochemical iron deficiency prevalence (23.3%) was observed in children aged 6-24 months, contrasting with dietary assessment findings.
Conclusions:
- Dietary iron intake assessment may overestimate the risk of iron deficiency in pediatric populations.
- Biochemical iron status assessment provides a more accurate measure of iron deficiency prevalence.
- Health program strategies should not rely solely on nutritional intake assessments; biochemical validation is recommended.
Abstract:
A random sample group of 300 children and adolescents (aged 0.5 to 16 years) from a Mediterranean town of Spain, were investigated as part of a health education program. Analysis of dietary iron intake and the biochemical parameters of iron status (red cell volume, erythrocyte protoporphyrin concentration, transferrin saturation percentage and serum ferritin) were measured. Based on dietary assessment, the percentage of children with iron intake levels below the Catalonia Recommended Daily Amounts varied from 24% to 77% and showed age and sex differences. The percentage of children with iron intakes below their own individual requirements varied between 7% and 41%. The age groups with the highest risk of iron deficiency were girls aged between 6 and 24 months, and boys aged between 13 and 16 years. However, based on the biochemically assessed iron status, the results revealed an overall prevalence of iron deficiency varying from 0 to 23.3%. The highest prevalence was encountered in boys and girls between 6 and 24 months (23.3%), compared with only 3.3% between 13 and 16 years. Despite conducting the investigation with the recommended controlled methodology, the results from dietary assessed risk of iron deficiency were significantly different from those assessed biochemically. Hence, caution is required when designing health programme strategies based exclusively on nutritional intake assessments.
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