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Updated: Aug 22, 2026

Estimation of Urinary Nanocrystals in Humans using Calcium Fluorophore Labeling and Nanoparticle Tracking Analysis
Published on: February 9, 2021
Can a relationship reflect the risk of calcium oxalate urolithiasis?
1Department de Biologia i Ciències de la Salut, Hospital General Virgen de LLuc (INSALUD), Palma de Mallorca, Spain.
Abstract:
Different mathematical expressions have been proposed in the literature with the aim to reflect the risk of calcium oxalate urolithiasis. Such expressions, as well as a number of new relationships proposed by us, have been evaluated in 76 patients and 34 normal subjects. Stone-formers were divided into two groups: patients with normal calcium and oxalate excretion and patients with hypercalciuria and/or hyperoxaluria. The results obtained were comparatively evaluated. Several formulae gave some acceptable results, but none of them were excellent. This can be explained by the fact that these discrimination indexes more or less reflect supersaturation and/or inhibition deficit, but none of them reflect promoting factors such as heterogeneous nucleation and/or aggregation capacity.
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