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Related Experiment Video

Updated: May 27, 2026

Vascular Balloon Injury and Intraluminal Administration in Rat Carotid Artery
09:41

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Published on: December 23, 2014

Spontaneous bilateral internal carotid artery dissection.

Srujan Ardhalapudi1, Victoria Addy, David Da Costa

  • 1Northern General Hospital, Geriatric Medicine, Hadfield Wing, Herries Road, Sheffield S5 7AU, UK.

BMJ Case Reports
|November 24, 2011
PubMed
Summary

This case report details a rare instance of spontaneous bilateral internal carotid artery dissection in a young woman presenting with stroke. Dual antiplatelet therapy was utilized, aligning with the CADISS trial protocols.

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Area of Science:

  • Neurology
  • Vascular Medicine
  • Cardiovascular Research

Background:

  • Spontaneous internal carotid artery dissection is a recognized cause of ischemic stroke in young adults.
  • Multiple cervical arterial dissections at initial presentation are infrequent.
  • Recurrence of dissection in previously unaffected arteries is a known phenomenon.

Purpose of the Study:

  • To report a rare case of spontaneous bilateral internal carotid artery dissection.
  • To discuss the clinical findings and management strategies for such a condition.
  • To highlight the use of dual antiplatelet therapy in managing cervical artery dissections.

Main Methods:

  • Case report review of a 42-year-old female patient.
  • Clinical assessment including neurological examination and imaging.
  • Treatment with dual antiplatelet therapy (aspirin and clopidogrel).
  • Patient management within a multidisciplinary team setting.

Main Results:

  • The patient presented with ischemic stroke and Horner syndrome.
  • Spontaneous bilateral internal carotid artery dissection was diagnosed.
  • Anticoagulation was withheld due to infarct size; dual antiplatelets were administered.
  • The patient demonstrated good progress and was discharged after 22 days.

Conclusions:

  • Bilateral internal carotid artery dissection is an uncommon but significant presentation of spontaneous cervical artery dissection.
  • Dual antiplatelet therapy is a viable management option, particularly within clinical trial contexts like CADISS.
  • Multidisciplinary care and community support are crucial for patient recovery.