Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Osteoclasts in Bone Remodeling

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

Bone Remodeling

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A chimaeric-pattern flap design for implantable Doppler surrogate monitoring: a novel placement technique.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2013

Same author

The dorsal metatarsal artery perforator flap.

Annals of plastic surgery·2013

Same author

Blindness resulting from orbital cellulitis following rhinoplasty.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2013

Same author

Motility differences in free colon and free jejunum flaps for reconstruction of the cervical esophagus.

Plastic and reconstructive surgery·2008

Same author

Use of stretch expanded polytetrafluoroethylene as a microvascular graft in a low-pressure situation.

Asian journal of surgery·2007

Search research articles

Related Experiment Video

Updated: May 27, 2026

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection

Published on: March 14, 2019

Accelerated osteomesh resorption: a case report.

Samuel Y M Ho¹, Vigneswaran Nallanthamby, Marcus T C Wong

¹Section of Plastic, Reconstructive, and Aesthetic Surgery, Department of General Surgery, Tan Tock Seng Hospital, Singapore.

Craniomaxillofacial Trauma & Reconstruction

|November 24, 2011

Summary

Orbital floor fractures from sports injuries can lead to complications. Early osteomesh resorption caused delayed enophthalmos and muscle entrapment, necessitating revision surgery for this facial fracture case.

Keywords:

Accelerated osteomesh resorption orbital floor fracture orbital floor implant

More Related Videos

A Simple Pit Assay Protocol to Visualize and Quantify Osteoclastic Resorption In Vitro

A Simple Pit Assay Protocol to Visualize and Quantify Osteoclastic Resorption In Vitro

Published on: June 16, 2022

Related Experiment Videos

Last Updated: May 27, 2026

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection

Published on: March 14, 2019

A Simple Pit Assay Protocol to Visualize and Quantify Osteoclastic Resorption In Vitro

A Simple Pit Assay Protocol to Visualize and Quantify Osteoclastic Resorption In Vitro

Published on: June 16, 2022

Area of Science:

Ophthalmology
Plastic Surgery
Trauma Surgery

Background:

Facial fractures, particularly orbital floor fractures, are common sequelae of blunt force trauma.
Large orbital floor defects necessitate surgical reconstruction to prevent orbital content herniation and associated complications.

Purpose of the Study:

To present a case of orbital floor fracture resulting from a sports-related injury.
To highlight the potential complications associated with using hand-cut osteomesh for orbital floor reconstruction.

Main Methods:

A 28-year-old male patient with a soccer-related orbital floor fracture underwent surgical repair.
The orbital floor defect was reconstructed using a hand-cut osteomesh implant.

Main Results:

The patient developed delayed enophthalmos and inferior rectus muscle entrapment post-operatively.
These complications were attributed to early resorption of the osteomesh implant.

Conclusions:

Early resorption of osteomesh can lead to delayed complications in orbital floor reconstruction.
Revision surgery may be required to address complications arising from implant resorption, emphasizing the need for careful material selection and monitoring.