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Notch Signaling in T-Cell Development and T-ALL

Xiaoyu Li1, Harald von Boehmer

  • 1Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA.

ISRN Hematology
|November 24, 2011
PubMed

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The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
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