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Updated: May 27, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
[Current status of blood pressure control in Japan and strategies for the better control]
Atsuhiko Takahashi1, Toshio Kushiro
1Nihon University Health Planning Center, Nihon University School of Medicine.
Insights
Achieving target blood pressure is crucial for hypertension management but often falls below 50%. Identifying and addressing factors like medication non-compliance and lifestyle issues is key to improving blood pressure control.
Area of Science:
- Cardiology
- Public Health
Context:
- Hypertension guidelines emphasize strict blood pressure control.
- Surveillance studies report target blood pressure achievement rates below 50%.
Purpose:
- To highlight the importance of identifying reasons for resistant hypertension.
- To advocate for comprehensive approaches to improve blood pressure control.
Summary:
- Poor medication compliance, lifestyle factors (obesity, diet, alcohol, sleep apnea), and co-administered drugs (NSAIDs, licorice) contribute to resistant hypertension.
- Physician attitudes also play a role in suboptimal blood pressure management.
- Identifying these contributing factors is the first step toward effective intervention.
Impact:
- Improved understanding of barriers to hypertension control.
- Informed strategies for healthcare professionals to enhance patient outcomes.
- Potential for increased rates of achieving target blood pressure goals.
Abstract:
Importance of strict blood pressure control in hypertension is stressed in guidelines. But rates of achieving target blood pressure in several surveillance studies are less than 50%. Poor compliance to medication, life style related problems such as obesity, excess salt and alcohol intake, sleep apnea and coadministered drugs such as NSAIDs or licorice, and physicians attitude to blood pressure control can be reasons for resistant hypertension. First step to improve the blood pressure control status is identifying reasons. To solve the identified problems, comprehensive approaches by health professionals are necessary.
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