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[Improvement of adherence in the treatment of hypertension]

Takuzo Hano1

  • 1Medical Education and Population-Based Medicine, Wakayama Medical University.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|November 25, 2011
PubMed

Insights

Poor medication adherence affects blood pressure control in many hypertensive patients. Interventions like pharmacy care, health promotion, and fixed-dose combination therapy can improve adherence and manage hypertension effectively.

Area of Science:

  • Cardiology
  • Pharmacology
  • Public Health

Context:

  • Hypertension management is a significant global health challenge, with poor blood pressure control rates affecting a majority of patients.
  • Medication non-adherence is a primary contributor to suboptimal hypertension treatment outcomes.
  • In Japanese hypertensive patients, medication non-adherence rates were 29.7%, with the non-adherent group exhibiting higher blood pressure levels.

Purpose:

  • To investigate the prevalence of medication non-adherence in Japanese hypertensive patients.
  • To identify factors contributing to antihypertensive medication non-adherence and discontinuation.
  • To evaluate the effectiveness of interventions in improving medication adherence and blood pressure control.

Summary:

  • Multiple factors influence medication adherence, including race, sex, age, cognitive function, side effects, and cost-benefit perceptions.
  • Young male subjects, patients with new visits, and those without comorbidities were more prone to discontinuing antihypertensive drugs.
  • Pharmacy care, active health promotion, and fixed-dose combination therapy demonstrated positive impacts on medication adherence and blood pressure control.

Impact:

  • Findings highlight the critical role of medication adherence in achieving effective hypertension management.
  • Interventions such as enhanced pharmacy care, health promotion, and simplified treatment regimens (fixed-dose combinations) are crucial for improving patient outcomes.
  • Addressing patient-specific factors and optimizing therapeutic strategies can lead to better blood pressure control and reduced cardiovascular risk.

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