Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Personalized whole-genome-based ctDNA dynamics during neoadjuvant therapy across breast cancer subtypes: results from MONITOR-Breast.

Future oncology (London, England)·2026
Same author

A novel algae oil-based emulsion enhances chemotherapy outcome in human cancer models.

Prostaglandins, leukotrienes, and essential fatty acids·2026
Same author

Impact of voxelotor discontinuation on patients with sickle cell disease.

British journal of haematology·2026
Same author

Quantitative and qualitative patient-reported analysis of misdiagnosis and/or late diagnosis of metastatic lobular cancer.

medRxiv : the preprint server for health sciences·2026
Same author

AI and the digital pathology revolution: clinical applications in cancer diagnosis and assessment.

Expert review of molecular diagnostics·2026
Same author

Long-term prognostic value of ctDNA in early breast cancer: insights from the neoadjuvant ABCSG-34 Trial.

NPJ breast cancer·2026
Same journal

In silico analysis suggests ELL2 as a survival-associated cross-tissue biomarker in gastric cancer.

Cancer biomarkers : section A of Disease markers·2026
Same journal

The clinical assessment of miR-34a and miR-135b panel as promising diagnostic biomarkers predict the risk of colorectal cancer: A case-control study.

Cancer biomarkers : section A of Disease markers·2026
Same journal

Integrative multi-omics analysis-based Mendelian randomization identifies association of DNA repair-related genes with oral cancer.

Cancer biomarkers : section A of Disease markers·2026
Same journal

Stage-specific biomarkers in triple-negative breast cancer: Preliminary findings from bioinformatics approaches.

Cancer biomarkers : section A of Disease markers·2026
Same journal

Development and verification of cell cycle-related gene markers for prognosis in bladder cancer.

Cancer biomarkers : section A of Disease markers·2026
Same journal

Detection of methylated SEPT9 DNA in peripheral blood for diagnosis of colorectal cancer.

Cancer biomarkers : section A of Disease markers·2026
See all related articles

Related Experiment Video

Updated: Jan 13, 2026

Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment
05:17

Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment

Published on: May 14, 2019

9.0K

Micrometastasis: detection methods and clinical importance.

Marija Balic1, Anthony Williams, Nadia Dandachi

  • 1Division of Oncology, Department of Internal Medicine, Medical University Graz, Austria.

Cancer Biomarkers : Section a of Disease Markers
|November 25, 2011
PubMed
Summary
This summary is machine-generated.

Detecting disseminated tumor cells (DTCs) is crucial for cancer management. Advanced technologies improve the detection of these rare circulating tumor cells (CTCs), offering significant prognostic value in various cancers.

More Related Videos

Long-term High-Resolution Intravital Microscopy in the Lung with a Vacuum Stabilized Imaging Window
07:19

Long-term High-Resolution Intravital Microscopy in the Lung with a Vacuum Stabilized Imaging Window

Published on: October 6, 2016

13.9K
Evaluation of Lung Metastasis in Mouse Mammary Tumor Models by Quantitative Real-time PCR
08:56

Evaluation of Lung Metastasis in Mouse Mammary Tumor Models by Quantitative Real-time PCR

Published on: January 28, 2016

10.3K

Related Experiment Videos

Last Updated: Jan 13, 2026

Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment
05:17

Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment

Published on: May 14, 2019

9.0K
Long-term High-Resolution Intravital Microscopy in the Lung with a Vacuum Stabilized Imaging Window
07:19

Long-term High-Resolution Intravital Microscopy in the Lung with a Vacuum Stabilized Imaging Window

Published on: October 6, 2016

13.9K
Evaluation of Lung Metastasis in Mouse Mammary Tumor Models by Quantitative Real-time PCR
08:56

Evaluation of Lung Metastasis in Mouse Mammary Tumor Models by Quantitative Real-time PCR

Published on: January 28, 2016

10.3K

Area of Science:

  • Oncology
  • Biomarkers
  • Cancer Metastasis

Background:

  • Metastatic disease is a key factor in cancer patient outcomes.
  • Disseminated tumor cells (DTCs), including circulating tumor cells (CTCs), indicate early metastatic spread.
  • Detecting these rare cells presents significant technical challenges.

Purpose of the Study:

  • To review current technologies for enriching and detecting DTCs and CTCs.
  • To discuss the clinical significance of DTCs in various cancer types.
  • To highlight future research directions in molecular characterization of tumor cells.

Main Methods:

  • Review of various enrichment strategies for DTCs/CTCs.
  • Exploration of molecular detection methods.
  • Discussion of clinical data on DTC/CTC detection.

Main Results:

  • Circulating tumor cells (CTCs) are emerging biomarkers with strong predictive and prognostic capacity in breast, prostate, lung, and colorectal cancers.
  • Diverse technologies exist for enhancing sensitivity and specificity in detecting rare tumor cells.
  • Clinical significance of DTCs varies across different cancer compartments.

Conclusions:

  • Future research should prioritize molecular characterization of DTCs/CTCs over mere detection.
  • Detailed analysis of tumor cell biology and heterogeneity is essential.
  • This approach holds potential for developing novel therapeutic strategies.