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Related Concept Videos

Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
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Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
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Related Experiment Video

Updated: May 27, 2026

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents
09:43

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents

Published on: August 10, 2014

Five years of Trials.

Douglas G Altman, Iain Hrynaszkiewicz, Curt D Furberg

    Trials
    |November 25, 2011
    PubMed
    Summary
    This summary is machine-generated.

    This editorial celebrates five years of the Trials journal, highlighting progress in clinical trial reporting and publication. It outlines future challenges, emphasizing innovation and the crucial publication of negative results.

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    Area of Science:

    • Clinical Trials Methodology
    • Scientific Publication Ethics

    Background:

    • The editorial introduces a special collection commemorating five years of the Trials journal.
    • It reviews the journal's progress towards its objectives since its inception in 2006.

    Discussion:

    • Key achievements include advancements in reporting clinical trial data and publishing diverse article types.
    • Challenges remain in further innovating trial reporting and encouraging the publication of negative results.

    Key Insights:

    • The journal has successfully promoted the publication of raw data and extended trial-related articles.
    • It has also facilitated the dissemination of 'lessons learned,' negative results, and educational content on ethics and reporting bias.

    Outlook:

    • Future efforts will focus on continued innovation in clinical trial reporting standards.
    • Emphasis will be placed on overcoming barriers to publishing negative trial outcomes to improve scientific transparency.