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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Assessment of the Abdomen II: Percussion01:18

Assessment of the Abdomen II: Percussion

Percussion is a fundamental technique used to assess the liver, spleen, and abdominal organs by tapping the abdomen and interpreting the resulting sounds. This method helps identify fluid, distention, and masses through variations in sound, such as the high-pitched tympany of air-filled areas and the dullness of solid masses. Understanding how to percuss these organs provides valuable information for healthcare professionals in diagnosing conditions early.
Percussion
Percussion is an essential...
Assessment of the Abdomen III: Palpation01:23

Assessment of the Abdomen III: Palpation

Palpation is a crucial tactile examination method for assessing abdominal organs and detecting conditions like tenderness, distention, masses, or fluid. It involves both light and deep palpation techniques, each serving specific diagnostic purposes. Light palpation helps identify tenderness and other surface-level indicators, while deep palpation locates and assess abdominal masses and organ boundaries. A skilled professional can gather valuable insights through palpation, including evaluating...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...

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Related Experiment Video

Updated: May 27, 2026

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
07:20

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Published on: December 21, 2012

Discriminating between simple and perforated appendicitis.

Mirelle E E Bröker1, Esther M M van Lieshout, Maarten van der Elst

  • 1Department of Surgery, Reinier de Graaf Groep, The Netherlands. m.broker@erasmusmc.nl

The Journal of Surgical Research
|November 25, 2011
PubMed
Summary

A new model predicts perforated appendicitis using C-Reactive Protein (CRP) levels and symptom duration. This aids in early diagnosis and treatment decisions for acute appendicitis.

Related Experiment Videos

Last Updated: May 27, 2026

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
07:20

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Published on: December 21, 2012

Area of Science:

  • Medical research
  • Clinical diagnostics
  • Surgical outcomes

Background:

  • Acute appendicitis diagnosis relies on history and labs.
  • Perforated appendicitis requires timely intervention.
  • Predictive models can improve diagnostic accuracy.

Purpose of the Study:

  • To develop a predictive model for perforated appendicitis.
  • To identify key clinical and laboratory predictors of perforation.
  • To enhance diagnostic strategies for appendicitis.

Main Methods:

  • Retrospective cohort study of 498 appendectomy patients.
  • Collected baseline characteristics, history, and lab data.
  • Utilized univariate and multivariable analyses to identify predictors.

Main Results:

  • Leukocyte count, CRP, ESR, symptom duration, and temperature were significant predictors.
  • Developed a model: P=1/(1+e(-(-2.788+0.012*CRP+0.207*days with complaints))).
  • CRP and symptom duration were key factors in the final model.

Conclusions:

  • Perforated appendicitis is predictable using CRP and symptom duration.
  • Findings may guide treatment choices between surgery and conservative management.
  • Early antibiotic initiation could be informed by this predictive model.