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Updated: May 27, 2026
05:51
Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
Published on: May 3, 2018
Association between arterial stiffness and pulmonary function in hypertensive patients
Hisashi Masugata1, Shoichi Senda, Hiroki Okada
1Department of Integrated Medicine, Kagawa University, 1750-1 Miki-cho, Kita-gun, Kagawa, Japan. masugata@med.kagawa-u.ac.jp
Summary
Arterial stiffness, measured by cardio-ankle vascular index (CAVI), is linked to poorer lung function and older pulmonary age in hypertensive patients. Monitoring CAVI may help predict chronic obstructive pulmonary disease (COPD) progression.
Area of Science:
- Cardiovascular Medicine
- Pulmonology
- Gerontology
Background:
- Arterial stiffness, assessed by cardio-ankle vascular index (CAVI), is a marker for arteriosclerosis.
- Pulmonary age, derived from pulmonary function tests, is a proposed diagnostic for chronic obstructive pulmonary disease (COPD).
Purpose of the Study:
- To investigate the association between CAVI and pulmonary function.
- To explore the correlation between vascular stiffness and pulmonary age in hypertensive individuals.
Main Methods:
- 45 hypertensive patients on medication for over a year were studied.
- Pulmonary function (FVC, FEV1/FVC ratio) and pulmonary age were assessed.
- Cardio-ankle vascular index (CAVI) was measured concurrently.
Main Results:
- CAVI correlated significantly with FEV1/FVC ratio (r=-0.399) and pulmonary age (r=0.559).
- CAVI was independently associated with reduced FEV1/FVC ratio (β=-0.418) and increased pulmonary age (β=0.514).
- Patients with higher pulmonary age exhibited significantly higher CAVI.
Conclusions:
- Increased CAVI is independently linked to diminished pulmonary function and advanced pulmonary age.
- Hypertensive patients with elevated CAVI may require monitoring for COPD progression.
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