Report of a patient chewing fentanyl patches who was titrated onto methadone
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Updated: May 27, 2026

Fentanyl Analog Screening using LC-TIMS-TOF MS/MS
Published on: November 8, 2024
Eric Dale1, Fleur Ashby, Kalyan Seelam
1St Catherine's Hospital, General Adult Psychiatry, Tickhill Road, Doncaster DN4 8QN, UK.
Abstract:
This case report discusses the clinical presentation and management of a patient presenting to substance misuse services reporting chewing fentanyl patches in addition to wearing them transdermally. The patient was successfully titrated onto methadone 30 mg. Only one previously reported case of an individual chewing fentanyl patches was found in the literature; no case reports were found where treatment involved titrating the patient onto methadone. The pharmacology and illicit use of fentanyl are also considered.
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