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Related Concept Videos

Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of endometrial...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
Oogenesis01:22

Oogenesis

Oogenesis,  the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...
Adrenal Gland Disorders01:27

Adrenal Gland Disorders

Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...

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Related Experiment Video

Updated: May 27, 2026

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
08:07

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Published on: April 5, 2024

Endocrine disorders & female infertility.

David Unuane1, Herman Tournaye, Brigitte Velkeniers

  • 1Department of Endocrinology, Universitair Ziekenhuis Brussel, UZ Brussel, Vrije Universiteit Brussel, Belgium.

Best Practice & Research. Clinical Endocrinology & Metabolism
|November 26, 2011
PubMed
Summary

Female infertility, often due to ovulatory disorders, involves complex interactions between the ovaries and endocrine system. Understanding these hormonal influences is key for accurate diagnosis and effective treatment strategies.

More Related Videos

Fertility Preservation in Patients with Severe Ovarian Dysfunction
12:03

Fertility Preservation in Patients with Severe Ovarian Dysfunction

Published on: March 25, 2021

Related Experiment Videos

Last Updated: May 27, 2026

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
08:07

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Published on: April 5, 2024

Fertility Preservation in Patients with Severe Ovarian Dysfunction
12:03

Fertility Preservation in Patients with Severe Ovarian Dysfunction

Published on: March 25, 2021

Area of Science:

  • Reproductive Endocrinology
  • Gynecology
  • Internal Medicine

Background:

  • Female infertility affects 37% of infertile couples, with ovulatory disorders being the most common cause.
  • Ovarian function is intricately linked with other endocrine organs, complicating infertility diagnosis.
  • Endocrine dysfunctions, including hypothalamic, pituitary, and thyroid issues, significantly impact female fertility.

Purpose of the Study:

  • To explore the intricate relationship between endocrine disorders and female infertility.
  • To present a diagnostic and management algorithm for female infertility.
  • To synthesize current evidence for approaching infertile patients with suspected endocrine involvement.

Main Methods:

  • Literature review of endocrine disorders affecting female fertility.
  • Analysis of diagnostic criteria for hypogonadotropic hypogonadism and hyperprolactinemia.
  • Evaluation of the impact of thyroid disorders, acromegaly, and Cushing's disease on fertility.

Main Results:

  • Ovulatory disorders are a primary driver of female infertility.
  • Hypothalamic dysfunction (hypogonadotropic hypogonadism), hyperprolactinemia, thyroid disorders, acromegaly, and Cushing's disease can all impair fertility.
  • Polycystic ovary syndrome and primary ovarian insufficiency are significant ovarian disorders impacting fertility.

Conclusions:

  • A systematic approach is crucial for diagnosing endocrine-related female infertility.
  • Recognizing the interplay between the endocrine system and ovaries aids in effective management.
  • Further research into novel treatments for primary ovarian disorders is ongoing.