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09:48
An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
Endocrine oncology in pregnancy.
1Centre for Endocrine and Diabetes Sciences, School of Medicine, Cardiff University, UK. lansdownaj@doctors.org.uk
Best Practice & Research. Clinical Endocrinology & Metabolism
|November 26, 2011
Summary
Diagnosing endocrine tumors during pregnancy is challenging as symptoms overlap with pregnancy. Management requires individualized, multidisciplinary care, balancing tumor type, stage, and patient wishes.
Area of Science:
- Endocrinology
- Obstetrics
- Oncology
Background:
- Endocrine tumors are rare in pregnant women, posing diagnostic and management challenges.
- Symptoms often mimic normal pregnancy or its complications like pre-eclampsia, requiring a high index of suspicion.
Purpose of the Study:
- To review the unique challenges in diagnosing and managing endocrine tumors during pregnancy.
- To highlight the need for individualized, multidisciplinary approaches to treatment decisions.
Main Methods:
- Review of existing literature on endocrine tumors in pregnancy.
- Discussion of diagnostic considerations and therapeutic options.
- Emphasis on shared decision-making between medical teams and patients.
Main Results:
- Limited evidence base necessitates personalized management strategies.
- Surgical timing varies: immediate for resectable adrenocortical carcinoma/phaeochromocytoma, postpartum for well-differentiated thyroid cancer.
- Medical therapy may be used to control tumor growth, hormone excess, and surgical/labor risks.
Conclusions:
- Management of endocrine tumors in pregnancy requires a tailored approach based on tumor specifics, gestational stage, and patient preferences.
- Multidisciplinary collaboration is crucial for optimal outcomes.
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