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DNA methylation as a biomarker for neuropsychiatric diseases

Sanxi Ai1, Lu Shen, Jifeng Guo

  • 1Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, PR China.

The International Journal of Neuroscience
|November 26, 2011
PubMed

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Epigenetic Regulation01:46

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Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...