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Published on: August 12, 2014
Carotid artery stenting and cardiac surgery in symptomatic patients
Jan Van der Heyden1, Danihel Van Neerven, Uday Sonker
1Department of Interventional Cardiology, St-Antonius Hospital, Nieuwegein, the Netherlands. janenvan@hotmail.com
Insights
Combining carotid artery stenting (CAS) and coronary artery bypass graft (CABG) surgery is feasible and safe for neurologically symptomatic patients. This approach offers a reliable alternative for high-risk individuals needing both procedures.
Area of Science:
- Cardiovascular Surgery
- Neurology
- Interventional Cardiology
Background:
- Patients undergoing coronary artery bypass graft (CABG) surgery with a history of stroke or transient ischemic attack face a significantly higher risk of perioperative stroke.
- Prophylactic carotid endarterectomy is often considered for neurologically symptomatic patients with significant carotid artery disease scheduled for CABG.
- Limited data exists on the combined outcomes of carotid artery stenting (CAS) and CABG in symptomatic patients.
Purpose of the Study:
- To assess the feasibility and safety of performing carotid artery stenting (CAS) followed by coronary artery bypass graft (CABG) surgery.
- To evaluate the combined outcomes in neurologically symptomatic patients requiring both procedures.
Main Methods:
- A prospective, single-center study analyzed 57 consecutive patients.
- Patients underwent CAS prior to undergoing cardiac surgery.
- Periprocedural and long-term outcomes were meticulously recorded and analyzed.
Main Results:
- Carotid artery stenting (CAS) achieved a high procedural success rate of 98%.
- The combined rate of death, stroke, and myocardial infarction within the study period was 12.3%.
- The combined rate of death and major stroke from CAS to 30 days post-cardiac surgery was 3.5%, with a 1.5% myocardial infarction rate.
Conclusions:
- This study presents the first single-center findings on combined CAS-CABG outcomes in symptomatic patients.
- The CAS-CABG strategy demonstrated reliable periprocedural and long-term results in this high-risk group.
- This approach may serve as a valuable alternative to combined surgical procedures, though further randomized trials are necessary.
Objectives:
The purpose of this study was to evaluate the feasibility and safety of the combined outcome of carotid artery stenting (CAS) and coronary artery bypass graft (CABG) surgery in neurologically symptomatic patients.
Background:
The risk of perioperative stroke in patients undergoing CABG who report a prior history of transient ischemic attack or stroke has been associated with a 4-fold increased risk as compared to the risk for neurologically asymptomatic patients. It seems appropriate to offer prophylactic carotid endarterectomy to neurologically symptomatic patients who have significant carotid artery disease and are scheduled for CABG. The CAS-CABG outcome for symptomatic patients remains underreported, notwithstanding randomized data supporting CAS for high-risk patients.
Methods:
In a prospective, single-center study, the periprocedural and long-term outcomes of 57 consecutive patients who underwent CAS before cardiac surgery were analyzed.
Results:
The procedural success rate of CAS was 98%. The combined death, stroke, and myocardial infarction rate was 12.3%. The death and major stroke rate from time of CAS to 30 days after cardiac surgery was 3.5%. The myocardial infarction rate from time of CAS to 30 days after cardiac surgery was 1.5%.
Conclusions:
This is the first single-center study reporting the combined outcome of CAS-CABG in symptomatic patients. The periprocedural complication rate and long-term results of the CAS-CABG strategy in this high-risk population support the reliability of this approach. In such a high-risk population, this strategy might offer a valuable alternative to the combined surgical approach; however, a large randomized trial is clearly warranted.
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