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Genetic approach to evaluation of hearing loss

Melinda Cohen1, John A Phillips

  • 1Division of Medical Genetics and Genomic Medicine, Vanderbilt University School of Medicine, DD-2205 Medical Center North, Nashville, TN 37232-2578, USA.

Otolaryngologic Clinics of North America
|November 26, 2011
PubMed

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Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...