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Related Concept Videos

Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...

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Related Experiment Video

Updated: May 27, 2026

In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time
09:19

In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time

Published on: May 24, 2020

Thromboembolic disorders in obstetrics.

Gabriella Gray1, Catherine Nelson-Piercy

  • 1Guy's and St Thomas' Foundation Trust, St Thomas' Hospital, Westminster Bridge Road, London, UK.

Best Practice & Research. Clinical Obstetrics & Gynaecology
|November 26, 2011
PubMed
Summary

Thromboembolic disorders are a major cause of preventable maternal death. Early risk assessment, pre-pregnancy planning, and timely thromboprophylaxis are crucial for reducing mortality in pregnant women.

Area of Science:

  • Obstetrics and Gynecology
  • Maternal Health
  • Thromboembolic Disorders

Background:

  • Thromboembolic disorders represent a significant cause of maternal mortality globally.
  • Recent data indicate a substantial reduction in deaths, highlighting the preventable nature of these events.

Purpose of the Study:

  • To emphasize the importance of formal risk factor assessment for thromboembolic disorders in pregnancy.
  • To advocate for proactive management strategies, including pre-pregnancy counseling and timely thromboprophylaxis.

Main Methods:

  • Formal assessment of risk factors (e.g., previous thromboembolic disorders, thrombophilia, obesity) at booking, delivery, or upon intercurrent complications.
  • Investigation of new chest symptoms in pregnant women, utilizing safe imaging modalities.

Related Experiment Videos

Last Updated: May 27, 2026

In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time
09:19

In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time

Published on: May 24, 2020

  • Empirical treatment initiation pending investigation completion.

    • Main Results:

    • Risk factor assessment should be a routine part of antenatal care.
    • Prophylaxis and treatment doses require careful adjustment based on maternal weight.
    • Early intervention, even in the first trimester, is vital.

    Conclusions:

    • Thromboembolic disorders are largely preventable causes of maternal mortality.
    • Comprehensive risk assessment and timely, weight-adjusted thromboprophylaxis are essential for improving maternal outcomes.