Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Effect of Aging on Tissues

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...

Renewal of Skin Epidermal Stem Cells

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...

Role of Skin in Vitamin D Synthesis

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

Tissue Renewal without Stem Cells

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...

The Skin Microbiota

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

30<sup>th</sup> Anniversary of Phytomedicine: Looking Back and Forth.

Phytomedicine : international journal of phytotherapy and phytopharmacology·2025

Same author

Reimagining ethnopharmacology with generative AI: Towards inclusive, ethical, and data-driven traditional medicine.

Pharmacological research·2025

Same author

Comprehensive Metabolomic and Bioactivity Profiling of Zingiberaceae Species From Manipur: Elucidating Antidiabetic and Antioxidant Mechanisms Through In Vitro and In Silico Approaches.

Phytochemical analysis : PCA·2025

Same author

Investigating the impact of Terminalia chebula, an underutilized functional fruit, on oral squamous cell carcinoma: Exploring cell death mechanisms.

Journal of ethnopharmacology·2025

Same author

Mechanistic insight into neuroprotective effect of standardized ginger chemo varieties from Manipur, India in scopolamine induced learning and memory impaired mice.

Metabolic brain disease·2025

Same author

Chrono-spatial reproductive phenology of <i>Swertia bimaculata</i> Hook.f. & Thomson ex C.B.Clarke reveals suitability as climate-changing bio-indicator along the Sikkim Himalayan altitude.

Heliyon·2024

Search research articles

Related Experiment Video

Updated: May 27, 2026

Quantifying the Modulation of Elastase Enzyme Activity Through Colorimetric Analysis

Quantifying the Modulation of Elastase Enzyme Activity Through Colorimetric Analysis

Published on: January 17, 2025

Bioactive compounds from natural resources against skin aging.

Pulok K Mukherjee¹, Niladri Maity, Neelesh K Nema

¹School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India. naturalproductm@gmail.com

Phytomedicine : International Journal of Phytotherapy and Phytopharmacology

|November 26, 2011

Summary

Natural phytomolecules offer a scientifically validated approach to combating skin aging. These botanical compounds protect against free radicals and environmental damage, promoting healthier, younger-looking skin without adverse reactions.

More Related Videos

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B

Published on: January 19, 2022

Related Experiment Videos

Last Updated: May 27, 2026

Quantifying the Modulation of Elastase Enzyme Activity Through Colorimetric Analysis

Quantifying the Modulation of Elastase Enzyme Activity Through Colorimetric Analysis

Published on: January 17, 2025

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B

Published on: January 19, 2022

Area of Science:

Dermatology and Cosmetology
Natural Product Chemistry
Molecular Biology

Background:

Skin aging, characterized by extracellular matrix degradation, manifests as wrinkles, laxity, and pigmentation changes.
Premature aging results from environmental factors, distinct from chronological aging.
Synthetic anti-aging products can cause adverse reactions like contact dermatitis and photo-allergic responses.

Purpose of the Study:

To review the scientific validation of natural products for anti-aging skincare.
To highlight the efficacy of phytomolecules in combating skin aging.
To explore the integration of botanical treatments with modern molecular techniques.

Main Methods:

Literature review of scientific validation for natural anti-aging compounds.
Analysis of phytomolecules' mechanisms of action against skin aging.
Examination of traditional herbal remedies in modern skincare.

Main Results:

Phytomolecules like aloin, curcumin, and asiaticoside scavenge free radicals and prevent water loss.
Many natural compounds offer a sun protection factor (SPF) of 15 or higher.
Botanical ingredients demonstrate significant potential in mitigating visible signs of skin aging.

Conclusions:

Natural products, backed by scientific evidence, present a safe and effective alternative to synthetic anti-aging treatments.
Combining herbal ingredients with advanced molecular techniques can enhance anti-aging benefits.
Phytomolecules contribute to healthier, younger-looking skin by protecting against aging factors.