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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

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Related Experiment Video

Updated: May 27, 2026

Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration
11:13

Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration

Published on: June 9, 2023

Vitamins B6 and cancer.

Sang Woon Choi1, Simonetta Friso

  • 1Tufts University, Medford/Somerville, MA, USA, sang.choi@tufts.edu.

Sub-Cellular Biochemistry
|November 26, 2011
PubMed
Summary

Vitamin B6 availability influences cancer risk, with high intake potentially reducing it and low intake increasing it. Marginal deficiencies, common in older adults and alcoholics, may promote cancer development.

Area of Science:

  • Nutritional Science
  • Oncology
  • Biochemistry

Background:

  • Epidemiologic and animal studies suggest vitamin B6 modulates cancer risk.
  • High dietary vitamin B6 intake may attenuate cancer risk, while low intake might increase it.
  • Overt vitamin B6 deficiency is rare, but marginal deficiencies are common, especially in the elderly and alcohol consumers.

Purpose of the Study:

  • To review current information on the relationship between vitamin B6 and cancer.
  • To explore the potential mechanisms by which vitamin B6 affects carcinogenesis.
  • To highlight the significance of marginal vitamin B6 deficiency in cancer risk.

Main Methods:

  • Literature review of epidemiologic studies.
  • Analysis of laboratory animal studies.

Related Experiment Videos

Last Updated: May 27, 2026

Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration
11:13

Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration

Published on: June 9, 2023

  • Synthesis of existing data on vitamin B6 and cancer.

    • Main Results:

    • Vitamin B6's role in cancer risk modulation is suggested but not fully elucidated.
    • Evidence indicates a potential inverse relationship between vitamin B6 levels and cancer risk.
    • Marginal vitamin B6 deficiency is a potential risk factor for carcinogenesis, particularly in vulnerable populations.

    Conclusions:

    • Vitamin B6 status is a potential factor in cancer prevention.
    • Further research is needed to clarify the precise mechanisms of vitamin B6 in cancer.
    • Addressing marginal vitamin B6 deficiency may be a relevant strategy in cancer risk reduction.