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[Resting heart rate and one year mortality association in patients with coronary heart disease]

E Umbrasiene, Ĭ Ventsloviene, R M Babarskiene

    Kardiologiia
    |November 29, 2011
    PubMed

    Insights

    Elevated resting heart rate (HR) significantly increases one-year mortality risk in coronary heart disease patients. This risk is further influenced by age and the acute or chronic nature of the heart condition.

    Area of Science:

    • Cardiology
    • Clinical Research
    • Risk Factor Analysis

    Context:

    • Coronary heart disease (CHD) poses a significant global health burden.
    • Resting heart rate (HR) is an emerging risk factor for cardiovascular events.
    • Understanding HR's impact on mortality is crucial for patient management.

    Purpose:

    • To investigate the association between admission resting heart rate (HR) and one-year survival in patients with coronary heart disease (CHD).
    • To analyze how gender, age, and clinical presentation (acute vs. chronic ischemic heart disease) modify this association.

    Summary:

    • A study of 3268 patients with acute myocardial infarction, unstable or stable angina found that a resting HR >= 67 bpm increased one-year mortality risk (p=0.017).
    • Significant interactions were observed between HR, age, and clinical expression of CHD.
    • Mortality risk was notably higher with HR >75 bpm in chronic CHD (p=0.015) and HR >71 bpm in acute coronary syndrome (p=0.016).
    • A resting HR >= 72 bpm more than doubled the one-year mortality risk in patients younger than 60 and older than 75 years (p=0.047).

    Impact:

    • Identifies specific resting heart rate thresholds associated with increased mortality in diverse CHD patient groups.
    • Highlights the importance of considering age and clinical presentation alongside HR for risk stratification.
    • Provides valuable data for refining treatment strategies and improving prognoses for coronary heart disease patients.

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