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Related Experiment Video

Updated: May 27, 2026

The TD Drive: A Parametric, Open-Source Implant for Multi-Area Electrophysiological Recordings in Behaving and Sleeping Rats

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Published on: April 26, 2024

Sleeping vs. loaded implants, long-term observations via a retrospective analysis.

K Marcelis¹, M Vercruyssen, E Nicu

¹Department of Periodontology, School of Dentistry, Oral Pathology & Maxillo-Facial Surgery, Faculty of Medicine, Catholic University Leuven, Kapucijnenvoer 33, B-3000, Leuven, Belgium.

Clinical Oral Implants Research

|November 29, 2011

Summary

Loaded dental implants experience significant bone loss initially, especially in the first year. Non-loaded implants show less bone loss over 12 years, suggesting early loading impacts bone levels.

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Noninvasive, High-throughput Determination of Sleep Duration in Rodents

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Published on: April 18, 2018

Area of Science:

Dental implantology
Periodontology
Biomaterials science

Background:

Marginal bone loss around dental implants is a multifactorial issue.
Theories include microbial factors, biomechanical loading, and host response.
Understanding early bone changes is crucial for long-term implant success.

Purpose of the Study:

To compare the long-term outcomes of loaded versus non-loaded (sleeping) dental implants.
To evaluate marginal bone level changes over a 12-year period using a split-mouth design.
To investigate the impact of initial loading on bone remodeling around implants.

Main Methods:

A 12-year split-mouth study involving 14 patients with overdentures.
Comparison of 28 loaded implants with 14 non-loaded (sleeping) implants in the mandible.
Intra-oral radiographs were used to assess marginal bone level changes over time.

Main Results:

Non-loaded implants exhibited significantly less bone loss than loaded implants over 12 years (P<0.007).
The primary difference in bone loss occurred within the first year of loading (0.8 mm vs. 0.1 mm).
Bone level changes were similar for both implant types after the initial loading phase.

Conclusions:

The initial months of functional loading significantly influence marginal bone levels around dental implants.
Subsequent bone level changes are more physiological after the initial adaptation period.
Early loading appears to be a critical factor in the adaptation of peri-implant bone.