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Updated: May 27, 2026
07:28
Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
Published on: July 10, 2018
Management of corneal perforation
Vishal Jhanji1, Alvin L Young, Jod S Mehta
1Centre for Eye Research Australia, University of Melbourne, Australia.
Survey of Ophthalmology
|November 29, 2011
Summary
Prompt diagnosis and treatment are crucial for corneal perforation, which may involve ocular tissue prolapse. Consider infectious keratitis, corneal xerosis, and vascular diseases, with surgery often necessary.
Area of Science:
- Ophthalmology
- Corneal disease research
Background:
- Corneal perforation presents a significant clinical challenge, potentially leading to ocular tissue prolapse.
- Prompt diagnosis and intervention are critical for managing this condition.
Purpose of the Study:
- To review the differential diagnosis of corneal perforation.
- To outline the primary treatment modalities for corneal perforations.
Main Methods:
- Literature review of corneal perforation causes and treatments.
- Analysis of diagnostic considerations and therapeutic strategies.
Main Results:
- Infectious keratitis is a common cause, but corneal xerosis and collagen vascular diseases warrant consideration.
- Medical therapy is adjunctive; surgical intervention is typically required.
Conclusions:
- Effective management of corneal perforation necessitates a thorough differential diagnosis and often surgical repair.
- Treatment options are tailored to perforation size and location, including gluing, amniotic membrane transplantation, and corneal transplantation.
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