Related Experiment Video

Updated: May 27, 2026

Fluorescence-Based Detection of FEN1 Nuclease Activity and Screening of Small-Molecule Inhibitors
05:46

Fluorescence-Based Detection of FEN1 Nuclease Activity and Screening of Small-Molecule Inhibitors

Published on: June 27, 2025

Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases

Jane A Grasby1, L David Finger, Susan E Tsutakawa

  • 1Centre for Chemical Biology, Department of Chemistry, Krebs Institute, University of Sheffield, Sheffield S3 7HF, UK. j.a.grasby@sheffield.ac.uk

Trends in Biochemical Sciences
|November 29, 2011
PubMed

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