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Behavioral problems in children with epilepsy in rural Kenya
Symon M Kariuki1, Amina Abubakar, Penny A Holding
1Center for Geographic Medicine Research-Coast, Kenya Medical Research Institute, Kilifi, Kenya. skariuki@kilifi.kemri-wellcome.org
Epilepsy & Behavior : E&B
|November 29, 2011
Summary
Children with epilepsy (CWE) in Kenya exhibit significantly more behavioral problems than healthy children. Active epilepsy, cognitive issues, and focal seizures are key risk factors, highlighting the need for integrated care.
Area of Science:
- Pediatric Neurology
- Child Psychiatry
- Global Health
Background:
- Epilepsy is a common neurological disorder in children, often associated with various comorbidities.
- Behavioral problems are frequently observed in children with epilepsy (CWE), impacting their quality of life and development.
- Understanding the prevalence and risk factors for behavioral issues in CWE is crucial for effective intervention, particularly in under-resourced regions.
Purpose of the Study:
- To document behavioral problems in children with epilepsy (CWE) in Kilifi, Kenya.
- To compare the prevalence of behavioral problems in CWE versus healthy controls.
- To identify independent risk factors associated with behavioral problems in CWE.
Main Methods:
- A cross-sectional study involving 108 CWE and 108 age-matched healthy controls in Kilifi, Kenya.
- Parental administration of a 15-item child behavioral questionnaire to assess behavioral problems.
- Statistical analysis, including t-tests and regression, to compare groups and identify covariates.
Main Results:
- Children with epilepsy (CWE) showed significantly higher mean scores for behavioral problems compared to controls (6.9 vs. 4.9, P<0.001).
- A greater proportion of CWE (49%) reported behavioral problems versus controls (26%).
- Active epilepsy, cognitive impairment, and focal seizures were identified as significant independent risk factors for behavioral problems in CWE.
Conclusions:
- Behavioral problems are highly prevalent in African children with epilepsy (CWE).
- Active epilepsy, cognitive impairment, and focal seizures are key predictors of these behavioral issues.
- Comprehensive clinical services in the region must integrate assessment and management of behavioral problems for CWE.
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