Related Experiment Video
Updated: May 27, 2026

08:13
In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation
Published on: November 11, 2025
Periorbital mass with cellulitis caused by dirofilaria
K Joseph1, A R Vinayakumar, S Criton
1Department of Microbiology, Amala Institute of Medical Sciences, Thrissur - 680 555, Kerala, India. katherinejc17@gmail.com
Indian Journal of Medical Microbiology
|November 29, 2011
Summary
Dirofilariasis, a zoonotic disease transmitted by mosquitoes, can cause eye lesions in humans. This case highlights ocular dirofilariasis presenting as a periorbital mass with cellulitis in India.
Area of Science:
- Veterinary Parasitology
- Ophthalmology
- Infectious Diseases
Background:
- Dirofilariasis is a zoonotic parasitic disease transmitted by mosquitoes, affecting animals and occasionally humans.
- Human infections can manifest as lung nodules, subcutaneous masses, or ocular lesions.
- The incidence of ocular dirofilariasis is increasing in India, particularly in Kerala.
Observation:
- A case of ocular dirofilariasis presenting with cellulitis as a periorbital mass is reported.
- The patient's symptoms indicated an accidental human infection with Dirofilaria parasites.
- The presentation mimicked other orbital inflammatory conditions.
Findings:
- The diagnosis confirmed ocular dirofilariasis, a rare manifestation of the zoonotic disease.
- The periorbital mass and cellulitis were attributed to the presence of the Dirofilaria parasite.
- Prompt diagnosis and management are crucial for preventing complications.
Implications:
- This case underscores the importance of considering zoonotic parasitic infections in orbital masses.
- Increased surveillance for ocular dirofilariasis is warranted in endemic regions.
- Understanding transmission dynamics is key to preventing human infections.
Related Concept Videos
Diphtheria
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Microbiome of the Eye
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
