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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Neuralgic amyotrophy associated with dengue fever: case series of three patients
1Department of Neurology, Chhatrapati Shahuji Maharaj Medical University, Lucknow, Uttar Pradesh, India. drrajeshverma32@yahoo.com
Abstract:
Dengue is an acute mosquito borne viral infection caused by one of the four distinct serotype of dengue viruses (type 1-4), belonging to flavivirus family. Dengue fever, an arboviral infection is known to cause various neurological complications. Commonly reported neurological manifestations associated with dengue infection are encephalopathy, myelopathy, stroke, Guillain-Barre syndrome and hypokalemic paralysis. Brachial amyotrophy associated with dengue infection were not described previously. Here, we describe three patients presenting with brachial neuritis associated with dengue infection. Dengue infection should be considered in the etiological list of brachial neuritis in dengue endemic areas, especially if preceded by history of febrile illness compatible with dengue illness.
Insights
Dengue virus infection can cause brachial neuritis, a rare neurological complication. This finding suggests considering dengue in the diagnosis of brachial neuritis, especially in endemic regions.
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Background:
- Dengue virus, a flavivirus, causes acute febrile illness with potential neurological complications.
- Known neurological manifestations include encephalopathy, myelopathy, stroke, Guillain-Barre syndrome, and hypokalemic paralysis.
Observation:
- This study describes three patients who developed brachial neuritis following dengue infection.
- Brachial amyotrophy (brachial neuritis) has not been previously documented as a dengue complication.
Findings:
- Dengue infection is identified as a potential cause of brachial neuritis.
- The three patients presented with symptoms consistent with brachial neuritis after a febrile illness.
Implications:
- Dengue should be included in the differential diagnosis of brachial neuritis in endemic areas.
- Early consideration of dengue in patients with febrile illness and neurological symptoms may improve diagnosis and management.
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