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Acute bacterial skin and skin structure infections: current perspective

Megha Shah1, Hetal D Shah

  • 1Medical College, Vadodara, Gujarat, India.

Indian Journal of Dermatology
|November 29, 2011
PubMed

Insights

Acute bacterial skin and skin structure infections (ABSSSI) are common and challenging due to rising antimicrobial resistance. Ceftaroline shows promise as a new agent to combat these resistant bacterial infections.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Pharmacology

Background:

  • Acute bacterial skin and skin structure infections (ABSSSI) represent a significant clinical challenge.
  • Treatment is complicated by increasing antimicrobial resistance, particularly from Gram-positive bacteria like methicillin-resistant Staphylococcus aureus (MRSA).

Purpose of the Study:

  • To highlight the growing problem of antimicrobial resistance in ABSSSI.
  • To introduce ceftaroline as a potential therapeutic agent against resistant bacterial pathogens.

Main Methods:

  • Literature review on ABSSSI epidemiology and resistance patterns.
  • Review of pharmacological data for ceftaroline efficacy.

Main Results:

  • Antimicrobial resistance is a primary concern in managing ABSSSI.
  • Ceftaroline demonstrates potential as a novel therapeutic option.

Conclusions:

  • There is an urgent need for new antimicrobial agents to treat ABSSSI.
  • Ceftaroline is a promising cephalosporin for addressing resistant bacterial infections.
Keywords:
Acute bacterial skin and skin structure infectionsceftarolinecomplicated skin infectionnewer cephalosporin

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